Organonitrogen Compounds
Medchemexpress LLC (R)-Nimodipine | 77940-92-2 | 99.9% | 1 MG
(R)-Nimodipine | 77940-92-2 | 99.9% | 1 MG
eMolecules 13887-51-9 | 2-BROMO-2-METHYL-1-MORPHOLINOPROPAN-1-ONE | AstaTech | MFCD12910756 | 236.109 | C8H14BrNO2 | 97.000 | CC(C)(Br)C(=O)N1CCOCC1 | 0.25g | 206677639
2-BROMO-2-METHYL-1-MORPHOLINOPROPAN-1-ONE | AstaTech | 13887-51-9 | MFCD12910756 | 236.109 | C8H14BrNO2 | 97.000 | CC(C)(Br)C(=O)N1CCOCC1 | 0.25g | 206677639
Apexbio Technology LLC Amlodipine Besylate 111470-99-6 10mM (in 1mL DMSO)
Amlodipine Besylate (CAS 111470-99-6) is a long-acting calcium channel blocker that reduces blood pressure primarily through inhibition of calcium ion influx via voltage-gated calcium channels Calcium channel modulation influences critical cellular signaling pathways In cortical neurons exposed to oxidative stress Amlodipine Besylate ( 5 M) preserves cellular viability by reducing oxidative damage enhancing pro-survival signals and suppressing apoptotic pathways It has also demonstrated proliferative effects on human epidermoid carcinoma (A431) cells Furthermore clinical studies indicate that Amlodipine Besylate decreases peripheral vascular resistance and myocardial oxygen demand in angina patients and effectively lowers arterial pressure in hypertensive feline models
eMolecules 1117-71-1 | METHYL 4-BROMOBUT-2-ENOATE | AstaTech | MFCD00000246 | 179.013 | C5H7BrO2 | 80.000 | COC(=O)\C=C\CBr | 25g | 457903317
METHYL 4-BROMOBUT-2-ENOATE | AstaTech | 1117-71-1 | MFCD00000246 | 179.013 | C5H7BrO2 | 80.000 | COC(=O)\C=C\CBr | 25g | 457903317
Sigma Aldrich Fine Chemicals Biosciences Amlodipine besylate European Pharmacopoeia (EP) Reference Standard | 111470-99-6 | MFCD00887594 |
Amlodipine besylate European Pharmacopoeia (EP) Reference Standard | Mol Wt: 567.05 | 111470-99-6 | MFCD00887594 |
Medchemexpress LLC To-1187 (TFA) | 98.4% | 795.72 | 50 MG
TO-1187 TFA is a selective HDAC6 PROTAC degrader with a DC50 of 5.81 nM. It functions by promoting the ubiquitination and degradation of HDAC6. This compound is suitable for use in research studying hematological malignancies and solid tumors. The compound is composed of an HDAC6 ligand, a CRBN ligase ligand, and a linker.
- Selective HDAC6 PROTAC degrader, exhibits a DC50 of 5.81 nM, indicating potent and specific degradation of HDAC6.
- Promotes ubiquitination and subsequent degradation of HDAC6.
- Useful in the study of hematological malignancies and solid tumors.
- Consists of a specific HDAC6 ligand, a CRBN ligase ligand, and a linker.
- Purity of 98.41%.
Medchemexpress LLC (S)-Nimodipine | 77940-93-3 | 99.9% | 418.44 | 1 MG
(S)-Nimodipine is an enantiomer of Nimodipine, a light-sensitive dihydropyridine calcium antagonist. This orally active and well-tolerated compound is utilized in the research of cerebrovascular disorders.
- Enantiomer of Nimodipine
- Orally active
- Dihydropyridine calcium antagonist
- Target: Calcium channel
- Pathway: Membrane transporter/ion channel; neuronal signaling
- Appearance: White to off-white solid
- Purity: 99.9%
- Molecular formula: C21H26N2O7
Selleck Chemical LLC Nimodipine S1747-1g
Nimodipine (BAY E 9736) is a dihydropyridine calcium channel blocker and an autophagy inhibitor used in the treatment of high blood pressure
Medchemexpress LLC PF-562271 besylate | 939791-38-5 | MFCD16038299 | 99.2% | 665.66 g·mol⁻¹ | C27H26F3N7O6S2 | 5 MG
PF-562271 besylate is a small-molecule, ATP-competitive, reversible inhibitor of focal adhesion kinase (FAK) and Pyk2 used in research to study FAK pathway modulation. It is supplied as the besylate salt for laboratory use and has been evaluated in preclinical and clinical studies.
- Potent ATP-competitive inhibitor of FAK and Pyk2 (IC50 1.5 nM and 13 nM).
- Reversible mechanism suitable for biochemical and cellular assays.
- Supplied as besylate salt for improved stability and handling.
- High chemical purity (99.17%) for reproducible results.
- Molecular weight 665.66 g·mol⁻¹, molecular formula C27H26F3N7O6S2.
- Intended for research use only; not for human or veterinary use.
